Yazar "Yigit, Serbulent" için listeleme
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Analysis of Endotheal Nitric Oxide Synthase Gene VNTR Variant in Turkish FMF Patients
Turkeli, Ozlem Sezer; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Galenos Publ House, 2022)Objective: Familial Mediterranean fever (FMF), caused by the MEFV gene encoding pyrin, is a prevalent monogenic autoinflammatory disease. Nitric oxide (NO), synthesized by nitric oxide synthase (NOS) is a gaseous free ... -
Analysis of Interleukin-1 Receptor Antagonist Variable Number Tandem Repeat Variant in Recurrent Aphthous Stomatitis
Tekcan, Akin; Yigit, Serbulent; Nursal, Ayse F.; Tumer, Mehmet K.; Yerliyurt, Kaan; Kuruca, Nilufer (Bentham Science Publ Ltd, 2021)Background/Aims: Recurrent aphthous stomatitis (RAS) is one of the common oral inflammatory diseases. As immunological and genetic factors have been held responsible for the pathogenesis of RAS, the objective of this study ... -
Association of eNOS gene 4a/4b VNTR and T786C polymorphism with Crimean-Congo hemorrhagic fever
Coskun, Umut Safiye Say; Yigit, Serbulent; Ozmen, Zeliha Cansel; Deveci, Koksal; Tekcan, Akin; Barut, Huseyin Sener; Dagcioglu, Yelda (Taylor & Francis Inc, 2023)The most common viral hemorrhagic fever is Crimean-Congo hemorrhagic fever (CCHF). Endothelial nitric oxide synthase (eNOS) gene polymorphisms have been linked to both hemorrhagic fevers and viral diseases. The study's ... -
Circadian clock gene variants may affect circadian fluctuations of anaerobic performance Gene variants and performance
Atan, Tulin; Unver, Saban; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Bayrakol Medical Publisher, 2021)Aim: Circadian rhythm (CR) may be followed by almost all biochemical and physiological processes that occur in the human body. Physical activities involving anaerobic fitness have displayed a dear CR. The aim of this study ... -
Effect of IL-6-174G/C and-572G/C variants on susceptibility to osteoarthritis in Turkish population
Yigit, Serbulent; Tekcan, Akin; Inanir, Ahmet; Nursal, Ayse Feyda; Akkanat, Songul; Tural, Ercan (Taylor & Francis Inc, 2022)Osteoarthritis (OA) is a complex disorder characterized by degenerative articular cartilage in which inflammatory mechanisms play a major role in the pathogenesis. Interleukin-6 (IL6), a multifunctional cytokine, can trigger ... -
Evaluating interleukin-6 levels and the rs1800795 variant in Turkish patients with COVID-19: a prospective cohort study
Sezer, Ozlem; Nursal, Ayse Feyda; Gunal, Ozgur; Gorgun, Selim; Tekcan, Akin; Unluguzel Ustun, Goksenin; Yigit, Serbulent (Taylor & Francis Inc, 2023)BackgroundCoronavirus disease 2019 (COVID-19) is a multisystem disease of global significance. Interleukin (IL)-6 is a soluble cytokine with a pleiotropic effect on inflammation and the immune response.ObjectivesInvestigate ... -
Lack of association between VNTR variant of the circadian gene (PER3) and major depressive disorder in a sample of a Turkish population
Yigit, Serbulent; Nursal, Ayse Feyda; Ozsoy, Filiz; Duman, Esra; Ustaoglu, Melih Sercan (Taylor & Francis Inc, 2023)Major depressive disorder (MDD), which is a prevalent psychiatric disorder, is characterized by sleep-wake disturbances. An underlying circadian rhythm disorder mainly may cause these disturbances. The study presented here ... -
Role of Interleukin-6 Gene Variants in the Development of Oral Squamous Cell Carcinoma
Gumusay, Ozge; Yigit, Serbulent; Nursal, Ayse Feyda; Tekcan, Akin; Dagmura, Hasan; Kuruca, Nilufer (Kare Publ, 2022)Oral squamous cell carcinoma (OSCC), with its low survival rates and increasing incidence, is due to various etiological factors including environmental, genetic, and epigenetic changes. Interleukin 6 (IL 6) is a cytokine ... -
VNTR Variant of the eNOS Gene and its Relationship with Osteoporosis in Postmenopausal Turkish Women
Nursal, Ayse F.; Yigit, Serbulent; Tekcan, Akin; Ozsoy, Asker Z.; Ates, Haci O. (Bentham Science Publ Ltd, 2021)Background: Osteoporosis (OP) is the most common type of systemic bone disease characterized by low bone mass and micro-structure deterioration of bone tissue, with a consequent increase in bone fragility and fracture risk. ...