Yazar "Tekcan, Akin" için listeleme
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Analysis of Endotheal Nitric Oxide Synthase Gene VNTR Variant in Turkish FMF Patients
Turkeli, Ozlem Sezer; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Galenos Publ House, 2022)Objective: Familial Mediterranean fever (FMF), caused by the MEFV gene encoding pyrin, is a prevalent monogenic autoinflammatory disease. Nitric oxide (NO), synthesized by nitric oxide synthase (NOS) is a gaseous free ... -
Analysis of Interleukin-1 Receptor Antagonist Variable Number Tandem Repeat Variant in Recurrent Aphthous Stomatitis
Tekcan, Akin; Yigit, Serbulent; Nursal, Ayse F.; Tumer, Mehmet K.; Yerliyurt, Kaan; Kuruca, Nilufer (Bentham Science Publ Ltd, 2021)Background/Aims: Recurrent aphthous stomatitis (RAS) is one of the common oral inflammatory diseases. As immunological and genetic factors have been held responsible for the pathogenesis of RAS, the objective of this study ... -
Association of ACE ID, MTHFR C677T, and MIF-173GC variants with the clinical course of COVID-19 patients
Tekcan, Akin; Cihangiroglu, Mustafa; Capraz, Mustafa; Capraz, Aylin; Yigit, Serbuelent; Nursal, Ayse Feyda; Menekse, Elif (Taylor & Francis Inc, 2023)The course of coronavirus disease-2019 (COVID-19) differs from person to person. The relationship between the genetic variations of the host and the course of COVID-19 has been a matter of interest. In this study, we ... -
Association of eNOS gene 4a/4b VNTR and T786C polymorphism with Crimean-Congo hemorrhagic fever
Coskun, Umut Safiye Say; Yigit, Serbulent; Ozmen, Zeliha Cansel; Deveci, Koksal; Tekcan, Akin; Barut, Huseyin Sener; Dagcioglu, Yelda (Taylor & Francis Inc, 2023)The most common viral hemorrhagic fever is Crimean-Congo hemorrhagic fever (CCHF). Endothelial nitric oxide synthase (eNOS) gene polymorphisms have been linked to both hemorrhagic fevers and viral diseases. The study's ... -
Circadian clock gene variants may affect circadian fluctuations of anaerobic performance Gene variants and performance
Atan, Tulin; Unver, Saban; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Bayrakol Medical Publisher, 2021)Aim: Circadian rhythm (CR) may be followed by almost all biochemical and physiological processes that occur in the human body. Physical activities involving anaerobic fitness have displayed a dear CR. The aim of this study ... -
Effect of IL-6-174G/C and-572G/C variants on susceptibility to osteoarthritis in Turkish population
Yigit, Serbulent; Tekcan, Akin; Inanir, Ahmet; Nursal, Ayse Feyda; Akkanat, Songul; Tural, Ercan (Taylor & Francis Inc, 2022)Osteoarthritis (OA) is a complex disorder characterized by degenerative articular cartilage in which inflammatory mechanisms play a major role in the pathogenesis. Interleukin-6 (IL6), a multifunctional cytokine, can trigger ... -
The effect of the MBL2 gene rs1800450 variant on COVID-19 development in Turkish patients
Capraz, Mustafa; Tekcan, Akin; Cihangiroglu, Mustafa; Nursal, Ayse Feyda; Capraz, Aylin; Menekse, Elif; Demir, Hatice Dortok (Taylor & Francis Inc, 2025)The coronavirus disease 2019 (COVID-19) is a recent pandemic occurring worldwide due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, spreading mainly through large respiratory droplets or maybe ... -
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats
Dizakar, Saadet Ozen Akarca; Saribas, Gulistan Sanem; Tekcan, Akin (Taylor & Francis Ltd, 2022)Diabetes mellitus (DM) is a serious and common in the world health problem that leads to different complications. Changes in oxidative stress and antioxidant capacity play an important role in the pathogenesis of DM. The ... -
Evaluating interleukin-6 levels and the rs1800795 variant in Turkish patients with COVID-19: a prospective cohort study
Sezer, Ozlem; Nursal, Ayse Feyda; Gunal, Ozgur; Gorgun, Selim; Tekcan, Akin; Unluguzel Ustun, Goksenin; Yigit, Serbulent (Taylor & Francis Inc, 2023)BackgroundCoronavirus disease 2019 (COVID-19) is a multisystem disease of global significance. Interleukin (IL)-6 is a soluble cytokine with a pleiotropic effect on inflammation and the immune response.ObjectivesInvestigate ... -
Genetic association of the BsmI variant of vitamin D receptor gene with risk of morbid obesity
Ozsoy, Seyma; Yigit, Serbulent; Nursal, Ayse Feyda; Ozsoy, Zeki; Dasiran, Mehmet Fatih; Daldal, Emin; Tekcan, Akin (Assoc Medica Brasileira, 2024)OBJECTIVE: The aim of this study was to evaluate the vitamin D receptor (VDR) BsmI variant in morbidly obese patients compared with healthy normal controls. METHODS: The study included 103 patients with morbid obesity and ... -
Investigation of the Effect of Silver Nanoparticles Obtained from Primula Vulgaris Extracts by Applying the Green Synthesis Method on MCF-7 Cells
Ciftci, Harun; Er Caliskan, Cigdem; Yazici, Burcu; Tekcan, Akin; Ozturk, Kubra (Iranian Institute of Research and Development in Chemical Industries, 2024)In recent years, the use of nanoparticles has gained significant attention in cancer research due to their unique properties and potential as targeted drug delivery systems. This study focuses on the synthesis and ... -
miR-146a rs2910164 (G/C) variant may predict morbid obesity risk in adults
Ozsoy, Zeki; Nursal, Ayse Feyda; Ozsoy, Seyma; Tekcan, Akin; Yigit, Serbulent (Taylor & Francis Inc, 2024)Obesity is a common public health problem associated with serious, life-threatening complications. MicroRNAs (miRs) have modulating roles in the immune and inflammatory systems. Therefore, this study aimed to analyze the ... -
The Relationship Between GPX1 Pro198Leu Manganese Superoxide Dismutase Ala16Val Variants and Obstructive Sleep Apnea Syndrome
Soyalic, Harun; Koseoglu, Handan Inonu; Zorlu, Duygu; Erturk, Arzu; Tekcan, Akin; Tuna, Elvan Evrim (Galenos Publ House, 2022)Objective: To investigate the association between obstructive sleep apnea syndrome (OSAS), glutathione peroxidase-1 (GPX1) Pro198Leu, and manganese superoxide dismutase (MnSOD) Ala16Val gene polymorphisms. Materials and ... -
Role of Interleukin-6 Gene Variants in the Development of Oral Squamous Cell Carcinoma
Gumusay, Ozge; Yigit, Serbulent; Nursal, Ayse Feyda; Tekcan, Akin; Dagmura, Hasan; Kuruca, Nilufer (Kare Publ, 2022)Oral squamous cell carcinoma (OSCC), with its low survival rates and increasing incidence, is due to various etiological factors including environmental, genetic, and epigenetic changes. Interleukin 6 (IL 6) is a cytokine ... -
Serum adiponectin and peroxisome proliferator-activated receptors- γ levels in obese patients with and without prediabetes
Gul, Mehmet Ali; Tozcu, Duygu; Tekcan, Akin; Capraz, Mustafa; Demir, Hatice Dortok (Assoc Medica Brasileira, 2024)OBJECTIVE: Obesity is an increasingly prevalent global health problem, which is generally caused by the increase in body fat mass above normal and observed in all societies. If the blood glucose level is higher than normal ... -
VNTR Variant of the eNOS Gene and its Relationship with Osteoporosis in Postmenopausal Turkish Women
Nursal, Ayse F.; Yigit, Serbulent; Tekcan, Akin; Ozsoy, Asker Z.; Ates, Haci O. (Bentham Science Publ Ltd, 2021)Background: Osteoporosis (OP) is the most common type of systemic bone disease characterized by low bone mass and micro-structure deterioration of bone tissue, with a consequent increase in bone fragility and fracture risk. ...
