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3-Imino derivative-sulfahydantoins: Synthesis, in vitro antibacterial and cytotoxic activities and their DNA interactions
Baskan, Ceren; Erturk, Aliye Gediz; Aydin, Birsen; Siriken, Belgin (Academic Press Inc Elsevier Science, 2022)Sulfahydantoins are five-membered rings found in the structure of chemicals that exhibit antibacterial, antiinflammatory, and anticonvulsant properties. They also activate serine protease enzymes that catalyze the hydrolysis ... -
Molecular characterization of extended-spectrum ?-lactamases-producing Enterobacteriaceae species in ground beef and chicken meat
Inat, Gokhan; Siriken, Belgin; Ciftci, Alper; Erol, Irfan; Baskan, Ceren; Yildirim, Tuba (Elsevier, 2023)The objectives of this study were i) to characterize extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) using pheno- and genotyping methods, ii) to evaluate the antimicrobial resistance pattern against ... -
Presence of quorum sensing system, virulence genes, biofilm formation and relationship among them and class 1 integron in carbapenem-resistant clinical Pseudomonas aeruginosa isolates
Baskan, Ceren; Siriken, Belgin; Tufekci, Enis Fuat; Kilinc, Cetin; Erturk, Omer; Erol, Irfan (Springer, 2022)Carbapenems are the most effective agents for treating clinical P. aeruginosa (PsA) infections. During an infection, a quorum-sensing (QS) system and its regulating virulence genes have a great role. The aim of the study ... -
Prevalence and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus in Foods of Animal Origin, Turkey
Siriken, Belgin; Yildirim, Tuba; Guney, Akif Koray; Erol, Irfan; Durupinar, Belma (INT ASSOC FOOD PROTECTION, 2016)In the present study, 175 coagulase-positive Staphylococcus (CPS) isolates recovered from samples of beef (n = 110), raw milk n 56), and fish (n = 9) were analyzed for methicillin resistance using MIC and PCR assays. ... -
Quorum sensing systems and related virulence factors in Pseudomonas aeruginosa isolated from chicken meat and ground beef
Inat, Gokhan; Siriken, Belgin; Baskan, Ceren; Erol, Irfan; Yildirim, Tuba; Ciftci, Alper (Nature Portfolio, 2021)The objective of this study was to evaluate 50 [chicken meat (n=45) and ground beef (n=5)] Pseudomonas aeruginosa isolates to determine the expression of the lasI and rhl QS systems, related virulence factors, and the ...