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dc.contributor.authorKaratayli, Ersin
dc.contributor.authorSoydemir, Ege
dc.contributor.authorAksoy, Zeynep Busra
dc.contributor.authorKizilpinar, Mehtap
dc.contributor.authorAltay Kocak, Aylin
dc.contributor.authorKaratayli, Senem Ceren
dc.contributor.authorYurdcu, Esra
dc.contributor.authorYildirim, Umut
dc.contributor.authorGuriz, Haluk
dc.contributor.authorBozdayi, Gulendam
dc.contributor.authorYurdaydin, Cihan
dc.contributor.authorIlhan, Osman
dc.contributor.authorYildirim, Yasin
dc.contributor.authorBozdayi, A. Mithat
dc.contributor.authorOguz, Acelya Yalcintas
dc.contributor.authorBaris, Ahmet
dc.contributor.authorAlp, Alpaslan
dc.contributor.authorAksozek, Alper
dc.contributor.authorSayiner, Arzu
dc.contributor.authorKaragul, Aydan
dc.contributor.authorOrdu, Aylin
dc.contributor.authorIstanbullu, Aye
dc.contributor.authorOtlu, Baris
dc.contributor.authorAridogan, Buket
dc.contributor.authorAksu, Burak
dc.contributor.authorBuruk, C. Kurtulus
dc.contributor.authorKarahan, Ceren
dc.contributor.authorGuney, Cakir
dc.contributor.authorToksoz, Devrim
dc.contributor.authorYildirim, Dilara
dc.contributor.authorColak, Dilek
dc.contributor.authorDaglar, Duygu Eren
dc.contributor.authorFindik, Duygu
dc.contributor.authorKas, Elif
dc.contributor.authorCaliskan, Emel
dc.contributor.authorZeyrek, Fadile Yildiz
dc.contributor.authorArslan, Fatma
dc.contributor.authorDemir, Feyza
dc.contributor.authorMilletli, Fikriye
dc.contributor.authorKibar, Filiz
dc.contributor.authorOzdincer, Furkan
dc.contributor.authorDundar, Gulnur
dc.contributor.authorArslan, Hande
dc.contributor.authorAgca, Harun
dc.contributor.authorAliskan, Hikmet Eda
dc.contributor.authorGuducuoglu, Huseyin
dc.contributor.authorFidan, Isil
dc.contributor.authorAkyar, Isin
dc.contributor.authorAfsar, Ilhan
dc.contributor.authorKaleli, Ilknur
dc.contributor.authorDonmez, Ismail
dc.contributor.authorYanik, Kemalettin
dc.contributor.authorMidilli, Kenan
dc.contributor.authorCubukcu, Kivanc
dc.contributor.authorOzdemir, Mehmet
dc.contributor.authorAcar, Melek
dc.contributor.authorYalinay, Meltem
dc.contributor.authorKuskucu, Mert Ahmet
dc.contributor.authorBakici, Mustafa Zahir
dc.contributor.authorAydin, Neriman
dc.contributor.authorYilmaz, Neziha
dc.contributor.authorCeken, Nihan
dc.contributor.authorZiyade, Nihan
dc.contributor.authorYilmaz, Nisel
dc.contributor.authorOzgumus, Osman Birol
dc.contributor.authorGitmisoglu, Ozlem
dc.contributor.authorDemirgan, Recep
dc.contributor.authorKesli, Recep
dc.contributor.authorGuckan, Ridvan
dc.contributor.authorSertoz, Ruchan
dc.contributor.authorAkgun, Sadik
dc.contributor.authorAksaray, Sebahat
dc.contributor.authorTezcan, Seda
dc.contributor.authorKaygusuz, Sedat
dc.contributor.authorGokahmetoglu, Selma
dc.contributor.authorMese, Sevim
dc.contributor.authorBayik, Seyit Ahmet
dc.contributor.authorAkcali, Sinem
dc.contributor.authorGurcan, Saban
dc.contributor.authorKarsligil, Tekin
dc.contributor.authorUs, Tercan
dc.contributor.authorOzekinci, Tuncer
dc.contributor.authorPilgir, Tulin
dc.contributor.authorAslan, Ugur
dc.contributor.authorDinc, Ugur
dc.contributor.authorCoskun, Umut Safiye Say
dc.contributor.authorCetinkol, Yeliz
dc.contributor.authorKeskin, Yusuf
dc.contributor.authorAyaydin, Zeynep
dc.contributor.authorToraman, Zulal Asci
dc.date.accessioned2019-09-01T13:04:15Z
dc.date.available2019-09-01T13:04:15Z
dc.date.issued2018
dc.identifier.issn0374-9096
dc.identifier.urihttps://dx.doi.org/10.5578/mb.67081
dc.identifier.urihttps://hdl.handle.net/20.500.12450/856
dc.descriptionWOS: 000454987700003en_US
dc.descriptionPubMed ID: 30522421en_US
dc.description.abstractMOTAKK, as a national external quality control program has been launched to evaluate the molecular detection of viral infections including HBV DNA and HCV RNA in molecular microbiology diagnostic laboratories in Turkey. This program is prepared in compliance with ISO 17043:2010 (Conformity assessment general requirements for proficiency testing) standards, and aims to take the place of external quality control programs from abroad, contributing to standardization and accuracy of molecular diagnostic tests in our country. The aim of this study was to evaluate 2015 and 2016 results of the MOTAKK External Quality Control Program for HBV DNA and HCV RNA viral load. The calls were announced on the web page of MOTAKK (www.motakk.org). The quality control samples were sent to participating laboratories in 2015 and 2016. Main stocks were prepared from patients with chronic hepatitis B and C who had viral load detection with reference methods according to WHO reference materials for viral load studies to improve quality control sera. From these main stocks, samples with different viral loads were prepared from dilutions of plasma with HBV, HCV, HAV, HIV, Parvovirus B19 and CMV negative serologic markers. Quality control samples were sent to the participating laboratories along with the negative samples in the cold chain. The laboratories accomplished the related tests within 2-3 weeks and entered their results on the MOTAKK web page. These results were analysed according to ISO 13528 (Statistical methods for use in proficiency testing by interlaboratory comparison) and scoring reports were created by a software developed by MOTAKK and sent to participating labs. Each laboratory evaluated their own results in comparison with the other laboratory results, reassessed the tests via observing the distance from the mean result and the reference values. The number of laboratories participating in the HBV DNA and HCV RNA external quality control program was 70-73 in 2015-2016. Participants were able to comply with the program tools, registering, entering results and receiving the results reports problem. In HBV panel, 72.6-89.1% and 84.7-90.3% of the participant laboratories were in 1 standard deviation (SD) in 2015-2016, respectively. In HCV panel, 70.8-89.1% and 84.7-90.3% of the participant laboratories were in 1 SD in 2015-2016, respectively. A national external quality control program for HBV DNA and HCV RNA in Turkey has been prepared for the first time with this project and implemented successfully. All the data provided in the MOTAKK external quality control program final report, compensate all the data provided by the quality control program final reports from abroad; additionally, the report allows comparison of used technologies and commercial products.en_US
dc.language.isoturen_US
dc.publisherANKARA MICROBIOLOGY SOCen_US
dc.relation.isversionof10.5578/mb.67081en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHBV DNAen_US
dc.subjectHCV RNAen_US
dc.subjectexternal quality controlen_US
dc.subjectviral loaden_US
dc.titleEvaluation of 2015-2016 MOTAKK HBV DNA and HCV RNA External Quality Assessment National Program Resultsen_US
dc.typearticleen_US
dc.relation.journalMIKROBIYOLOJI BULTENIen_US
dc.authoridYurdcu, Esra -- 0000-0002-1441-6408; Sayiner, Ayca -- 0000-0001-6750-2353; Kibar, Filiz -- 0000-0003-2983-2399; Otlu, Baris -- 0000-0002-6220-0521; BOZDAYI, ABDURRAHMAN MITHAT -- 0000-0002-2785-1804en_US
dc.identifier.volume52en_US
dc.identifier.issue4en_US
dc.identifier.startpage348en_US
dc.identifier.endpage366en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.department-temp[Karatayli, Ersin -- Kizilpinar, Mehtap -- Altay Kocak, Aylin -- Karatayli, Senem Ceren -- Yurdcu, Esra -- Bozdayi, A. Mithat] Ankara Univ, Hepatol Inst, Ankara, Turkey -- [Soydemir, Ege -- Aksoy, Zeynep Busra] Ankara Univ, Biotechnol Inst, Ankara, Turkey -- [Altay Kocak, Aylin] Baskent Univ, Dept Med Microbiol, Fac Med, Ankara, Turkey -- [Yildirim, Umut] Tomurcuk Technol, Cyberpk, Ankara, Turkey -- [Guriz, Haluk] Ankara Univ, Fac Med, Cebeci Cent Lab, Ankara, Turkey -- [Bozdayi, Gulendam] Gazi Univ, Dept Med Microbiol, Fac Med, Ankara, Turkey -- [Yurdaydin, Cihan] Ankara Univ, Div Gastroenterol, Fac Med, Ankara, Turkey -- [Ilhan, Osman] Ankara Univ, Div Hematol, Fac Med, Ankara, Turkey -- [Yildirim, Yasin] Ankara Univ, Therapeut Apheresis Ctr, Div Hematol, Fac Med, Ankara, Turkey -- [Oguz, Acelya Yalcintas] Iontek Lab, Istanbul, Turkey -- [Baris, Ahmet] RTA Lab, Kocaeli, Turkey -- [Alp, Alpaslan] Hacettepe Univ, Hastaneleri Merkez Lab, Ankara, Turkey -- [Aksozek, Alper] Mugla Sitki Kocman Univ EAH, Mikrobiyoloji Lab, Mugla, Turkey -- [Sayiner, Arzu] Dokuz Eylul Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Izmir, Turkey -- [Karagul, Aydan] Antalya Egitim & Arastirma Hastanesi, Antalya, Turkey -- [Ordu, Aylin] Sisli Florence Nightingale Hastanesi, Mol Mikrobiyoloji Lab, Istanbul, Turkey -- [Istanbullu, Aye] Medipol Hastanesi, Istanbul, Turkey -- [Otlu, Baris] Malatya Univ, Tibbi Mikrobiyoloji AD, Malatya, Turkey -- [Aridogan, Buket] Suleyman Demirel Univ, Tibbi Mikrobiyoloji AD, Isparta, Turkey -- [Aksu, Burak] Marmara Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Istanbul, Turkey -- [Buruk, C. Kurtulus] KATU, Tip Fak, Tibbi Mikrobiyoloji AD, Trabzon, Turkey -- [Karahan, Ceren] Ankara Univ, Tip Fak, Ibn I Sina Hastanesi Merkez Mikrobiyoloji Lab, Ankara, Turkey -- [Guney, Cakir] Ozel SYNLAB Merkezi Lab, Ankara, Turkey -- [Toksoz, Devrim] Referans Klin Lab, Istanbul, Turkey -- [Yildirim, Dilara] Sivas Numune Hastanesi, Mikrobiyoloji Lab, Sivas, Turkey -- [Colak, Dilek] Akdeniz Univ Hastanesi, Merkez Lab, Antalya, Turkey -- [Daglar, Duygu Eren] Aydin Devlet Hastanesi, Tibbi Mikrobiyoloji Lab, Aydin, Turkey -- [Findik, Duygu -- Aslan, Ugur] Selcuk Univ, Tibbi Mikrobiyoloji Lab, Tip Fak, Konya, Turkey -- [Kas, Elif] Ankara 2 Bolge KHB Genel Sekreterligi, Ankara, Turkey -- [Caliskan, Emel] Duzce Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Duzce, Turkey -- [Zeyrek, Fadile Yildiz] Harran Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Sanliurfa, Turkey -- [Arslan, Fatma] Kayseri Egitim & Arastirma Hastanesi, Kayseri, Turkey -- [Demir, Feyza] SB SBU Van EAH Mikrobiyoloji Bolumu, Van, Turkey -- [Milletli, Fikriye] Ahi Evran Univ, EAH Mikrobiyoloji Lab, Kirsehir, Turkey -- [Kibar, Filiz] Cukurova Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Adana, Turkey -- [Ozdincer, Furkan] Gelisim Tip Lab, Istanbul, Turkey -- [Dundar, Gulnur] Ctr Lab Mol Mikrobiyoloji, Istanbul, Turkey -- [Arslan, Hande] Baskent Univ, Enfeksiyon Hastaliklari & Klin Mikrobiyoloji AD, Ankara, Turkey -- [Agca, Harun] Uludag Univ, Tip Fak, Mikrobiyoloji AD, Bursa, Turkey -- [Aliskan, Hikmet Eda] Baskent Univ, Tibbi Mikrobiyoloji AD, Adana Uygulama & Arastirma Merkezi Mikrobiyoloji, Adana, Turkey -- [Guducuoglu, Huseyin] Yuzuncu Yil Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Van, Turkey -- [Fidan, Isil] Gazi Univ, Tip Fak, Tibbs Mikrobiyoloji AD, Ankara, Turkey -- [Akyar, Isin] Acibadem Labmed Mikrobiyoloji Lab, Istanbul, Turkey -- [Afsar, Ilhan] IKCU Ataturk EAH Tibbi Mikrobiyoloji Lab, Izmir, Turkey -- [Kaleli, Ilknur] Pamukkale Univ, Tibbi Mikrobiyoloji Merkez Lab, Denizli, Turkey -- [Donmez, Ismail] Usak Devlet Hastanesi Mikrobiyoloji Lab, Usak, Turkey -- [Yanik, Kemalettin] Ondokuz Mayis Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Samsun, Turkey -- [Midilli, Kenan -- Kuskucu, Mert Ahmet] Istanbul Univ, Cerrahpa Tip Fak, Tibbi Mikrobiyoloji AD, Istanbul, Turkey -- [Cubukcu, Kivanc] Trabzon Kanuni EAH Klin Mikrobiyoloji Lab, Trabzon, Turkey -- [Ozdemir, Mehmet] Necmettin Erbakan Univ Hastanesi, Tibbi Mikrobiyoloji AD, Konya, Turkey -- [Acar, Melek] Samsun Egitim & Arastirma Hastanesi, Mikrobiyoloji Lab, Samsun, Turkey -- [Yalinay, Meltem] Gazi Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Ankara, Turkey -- [Bakici, Mustafa Zahir] Cumhuriyet Univ, Uygulama & Arastirma Hastanesi, Mikrobiyoloji Lab, Sivas, Turkey -- [Aydin, Neriman] Adnan Menderes Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Aydin, Turkey -- [Yilmaz, Neziha] Bozok Univ, Mikrobiyoloji AD, Yozgat, Turkey -- [Ceken, Nihan] Balikesir Devlet Hastanesi, Mikrobiyoloji Lab, Balikesir, Turkey -- [Ziyade, Nihan] Istanbul Adli Tip Kurumu Baskanligi Postmortem Mi, Istanbul, Turkey -- [Yilmaz, Nisel] Tepecik Egitim & Arastirma Hastanesi, Tibbi Mikrobiyoloji Lab, Izmir, Turkey -- [Ozgumus, Osman Birol] Recep Tayyip Erdogan Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Rize, Turkey -- [Gitmisoglu, Ozlem] Necip Fazil Sehir Hastanesi, Mikrobiyoloji Lab, Kahramanmaras, Turkey -- [Demirgan, Recep] Anatolia Genet Lab, Istanbul, Turkey -- [Kesli, Recep] Afyon Kocatepe Univ, Tibbi Mikrobiyoloji AD, Afyon, Turkey -- [Guckan, Ridvan] Amasya Univ, Sabuncuoglu Serefeddin EAH, Mikrobiyoloji Klin, Amasya, Turkey -- [Sertoz, Ruchan] Ege Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Izmir, Turkey -- [Akgun, Sadik] Adiyaman Univ, EAH Tibbi Mikrobiyoloji Lab, Adiyaman, Turkey -- [Aksaray, Sebahat] Haydarpasa Numune Hastanesi, Tibbi Mikrobiyoloji Lab, Istanbul, Turkey -- [Tezcan, Seda] Mersin Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Mersin, Turkey -- [Kaygusuz, Sedat] Kirikkale Univ, Enfeksiyon Hastaliklan & Klin Mikrobiyoloji AD, Kirikkale, Turkey -- [Gokahmetoglu, Selma] Erciyes Univ, Tip Fak, Mikrobiyoloji AD, Kayseri, Turkey -- [Mese, Sevim] Istanbul Univ, Istanbul Tip Fak, Tibbi Mikrobiyoloji AD, Istanbul, Turkey -- [Bayik, Seyit Ahmet] Adana Numune EAH, Tibbi Mikrobiyoloji Lab, Adana, Turkey -- [Akcali, Sinem] Celal Bayar Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Manisa, Turkey -- [Gurcan, Saban] Trakya Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Tekirdag, Turkey -- [Karsligil, Tekin] Gaziantep Univ, Tibbi Mikrobiyoloji AD, Gaziantep, Turkey -- [Us, Tercan] Eskisehir Osmangazi Univ, Tibbi Mikrobiyoloji AD, Eskisehir, Turkey -- [Ozekinci, Tuncer] Dicle Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Diyarbakir, Turkey -- [Pilgir, Tulin] Viromed Lab, Ankara, Turkey -- [Dinc, Ugur] Corlu Devlet Hastanesi, Mikrobiyoloji Lab, Corlu, Turkey -- [Coskun, Umut Safiye Say] TOKAT GOP Univ Hastanesi, Mikrobiyoloji Lab, Tokat, Turkey -- [Cetinkol, Yeliz] Ordu Univ EAH, Tibbi Mikrobiyoloji Lab, Ordu, Turkey -- [Keskin, Yusuf] Cukurova Devlet Hastanesi, Mikrobiyoloji Lab, Adana, Turkey -- [Ayaydin, Zeynep] Gazi Yasargil EAH, Mikrobiyoloji Lab, Diyarbakir, Turkey -- [Toraman, Zulal Asci] Firat Univ, Tip Fak, Tibbi Mikrobiyoloji AD, Elazig, Turkeyen_US


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