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dc.contributor.authorHundur D.O.
dc.contributor.authorIdil O.
dc.contributor.authorKandemir N.
dc.contributor.authorGul M.
dc.contributor.authorKonar V.
dc.date.accessioned2019-09-01T12:50:06Z
dc.date.available2019-09-01T12:50:06Z
dc.date.issued2018
dc.identifier.issn1018-4619
dc.identifier.urihttps://hdl.handle.net/20.500.12450/524
dc.description.abstractThe aim of this study was evaluation of invitro antioxidant and antimicrobial activities of Leucojum aestivum extracts, and determination of the total phenolic compounds of Leucojum aestivum by reverse-phase high-performance liquid chromatography. Leucojum aestivum is known as summer snowflake. It is the only single species of Leucojum genus in Turkey. This species contains various alkaloids in the bulbs and has beautiful flowers. Therefore, it is used as ornamental and economic plant in Turkey and in many parts of the world. This species is categorized in the group of medicinal, aromatic and ornamental plants in Turkey. We prepared extracts of below- and above-ground parts of the plant with three solvents, namely ethanol, methanol, and hexane, to analyze its potential as a medicinal plant. Ethanolic and methanolic extracts of Leucojum aestivum have been found to demonstrate antioxidant and antimicrobial activities against Gram-positive and Gram-negative bacteria, and yeast. In conclusion, the high phenolic and flavonoid content of the extract exhibits high antioxidant activity, and antimicrobial activity results are associated with DNA interaction. © by PSP.en_US
dc.description.sponsorshipAmasya Üniversitesien_US
dc.description.sponsorshipThis study was performed within the scope of the project of FMB-BAP-14-070 supported by Amasya University and special thanks also go to Amasya University Central Research Laboratory.en_US
dc.language.isoengen_US
dc.publisherParlar Scientific Publicationsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDNA interactionen_US
dc.subjectLeucojum aestivum, in-vitro antioxidant, dpph radical scavenging activity, total flavonoid content, in-vitro antimicrobialen_US
dc.titlePhytochemical screening and in-vitro antioxidant, antimicrobial activity and DNA interaction of Leucojum aestivumen_US
dc.typearticleen_US
dc.relation.journalFresenius Environmental Bulletinen_US
dc.identifier.volume27en_US
dc.identifier.issue10en_US
dc.identifier.startpage6704en_US
dc.identifier.endpage6710en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.department-tempHundur, D.O., Biology Department, Science-Art Faculty, Amasya University, Amasya, 05100, Turkey -- Idil, O., Pre-School Education, Educational Faculty, Amasya University, Amasya, 05100, Turkey -- Kandemir, N., Pre-School Education, Educational Faculty, Amasya University, Amasya, 05100, Turkey -- Gul, M., Chemistry Department, Science-Art Faculty, Amasya University, Amasya, 05100, Turkey -- Konar, V., Biology Department, Science-Art Faculty, Amasya University, Amasya, 05100, Turkeyen_US


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