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dc.contributor.authorDemir, Hale
dc.contributor.authorCin, Selcuk
dc.contributor.authorCitgez, Sinharib
dc.contributor.authorUygun, Nesrin
dc.date.accessioned2024-03-12T19:34:50Z
dc.date.available2024-03-12T19:34:50Z
dc.date.issued2021
dc.identifier.issn1018-5615
dc.identifier.issn1309-5730
dc.identifier.urihttps://doi.org/10.5146/tjpath.2020.01502
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/523104
dc.identifier.urihttps://hdl.handle.net/20.500.12450/2742
dc.description.abstractVillous adenomas (VAs) in the female urethra are rare with only seven cases in the English literature to our knowledge. In patients with bladder augmentation cystoplasty, the neoplasia development risk increases and most of these develop in the neobladder or anastomosis line. Only two cases of VA developing from the native bladder mucosa have been reported. Physical examination of a 76-year-old female who had a history of augmentation cystoplasty revealed a caruncula-like structure protruding from the urethral meatus. The urinary USG showed that the lesion had no relation with the bladder. The lesion was excised. Microscopically, it consisted of villous structures covered with pseudostratified intestinal type epithelium. Low-grade dysplasia was present in the epithelium but high-grade dysplasia or in-situ/invasive carcinoma was not observed. Immunohistochemical study showed positivity for CK7, CK20, EMA, CEA and CDX2. The case was reported as VA of the urethra. We presented the first VA case arising in the urethra of a female patient with intestinal bladder augmentation. Excision is curative for pure VAs. Transformation to carcinoma or recurrence has not been reported. However, in one third of the cases, a malignant tumor may accompany the lesion. Therefore, all excision material should be examined carefully. Routine endoscopic follow-up should be performed in cases with bladder augmentation.en_US
dc.language.isoengen_US
dc.publisherFederation Turkish Pathology Socen_US
dc.relation.ispartofTurkish Journal Of Pathologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVillous adenomaen_US
dc.subjectUrethraen_US
dc.subjectUrinary tracten_US
dc.subjectBladder augmentationen_US
dc.titleVillous Adenoma Arising in the Urethra of a Female with Bladder Augmentation History: A Case Report and Review of the Literatureen_US
dc.typereviewArticleen_US
dc.departmentAmasya Üniversitesien_US
dc.authoridDemir, Hale/0000-0002-0773-2824
dc.identifier.volume37en_US
dc.identifier.issue2en_US
dc.identifier.startpage161en_US
dc.identifier.endpage166en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-85106539781en_US
dc.identifier.trdizinid523104en_US
dc.identifier.doi10.5146/tjpath.2020.01502
dc.department-temp[Demir, Hale] Amasya Univ, Sch Med, Dept Pathol, Amasya, Turkey; [Cin, Selcuk] Bagcilar Training & Res Hosp, Istanbul, Turkey; [Citgez, Sinharib] Istanbul Univ Cerrahpasa, Cerrahpasa Sch Med, Dept Urol, Istanbul, Turkey; [Uygun, Nesrin] Istanbul Univ Cerrahpasa, Cerrahpasa Sch Med, Dept Pathol, Istanbul, Turkeyen_US
dc.identifier.wosWOS:000648892700009en_US
dc.identifier.pmid32779155en_US
dc.authorwosidDemir, Hale/AAG-2277-2019


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