Yazar "Yıldırım, Tuba" için TR-Dizin İndeksli Yayınlar Koleksiyonu listeleme
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Analyses of the relationships among biofilm activity, antibiotic resistance and expressions of SHV, TEM, CTXand IntI in Klebsiella pneumoniae
Aim: Klebsiella pneumoniae as an opportunistic pathogen is responsible for nosocomial, urinary tract infections, pneumonia, bacteremia, liver abscesses, and respiratory and blood infections in patients. The aim of our study ... -
Antiproliferative Activity of Pyrrolidine Derivatives compound in Colon Cancer Cells
Gül, Melek; Yıldırım, Tuba; Mesci, Seda (2022)Objective: Anti-cancer drug research plays an important role for chemotherapeutic treatments in various types of cancer. Pyrolidine derived compounds have been reported by many researchers to be a potent anti-cancer compound. ... -
ATP?Binding Cassette Transporters Mediated Chemoresistance in MCF-7 Cells: Modulation by PhTAD-Substituted Dihydropyrrole Compounds
Purpose: ABC proteins transport many substrates such as antibiotics and drugs. Increase of ABCs lead chemoresistance in can-cer.In view of this information, in our study, we planned to investigate both PhTAD-substituted ... -
Effects of Sulfur Containing Glycine Imine Derivatives Compounds on Multidrug Resistance Proteins (MRPs) and Apoptosis Mechanism in MCF-7 and DLD-1 Cell Lines
Gül, Melek; Yıldırım, Tuba; Mesci, Seda; Yazgan, Burak; b, a (2022)Objective: Glutathione (GSH) is a tripeptide consisting of glycine, glutamic acid and cysteine. If the sulfur containing amino acids like methionine and cysteine increase in the cells, the level of GSH increases. GSH is ... -
PhTAD-Substituted Dihydropyrrole Compounds Regulate Apoptotic Cell Death in MCF-7 Cells
Breast cancer is the most common type of cancer amongst women. Apoptosis is known as a programmed cell death and this mechanism induces cancer cell death. Dihydropyrrole compounds contain a heterocyclic structure and these ...