Theoretical Production of Radiopharmaceuticals Used in Mycardial Perfusion Scintigraphy

Abstract

Myocardial perfusion scintigraphy, is an imaging technique used for diagnostics of coronary artery disease in people by evaluating the amount of blood reaching the heart muscle. During myocardial perfusion scintigraphy a radiopharmaceutical is injected into the patient and after a period of time a series of images are acquired using gamma camera rotated by 180 degrees around the patient. The distribution of the radiopharmaceutical is then determined using the technology of single photon emission computed tomography. The most commonly used agents in myocardial perfusion scintigraphy radiopharmaceuticals are Tl-201 and Tc-99m. The production of such radiopharmaceuticals containing Tl-201 and Tc-99m has been examined by this study. This study was performed using Monte Carlo nuclear reaction simulation code TALYS 1.6.