Yazar "Uludag, Yildiz" için listeleme
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Biological Activity of New Cyclophosphazene Derivatives Including Fluorenylidene-Bridged Cyclophosphazenes
Yildirim, Tuba; Senkuytu, Elif; Ergene, Emel; Bilgin, Kemal; Uludag, Yildiz; Ciftci, Gonul Yenilmez (WILEY-V C H VERLAG GMBH, 2018)In this study, new cyclophosphazene compounds were synthesized characterized and their biological activity studies were performed. The structural investigations of the compounds were verified by elemental analyses, mass ... -
DNA interaction analysis of fluorenylidene double bridged cyclotriphosphazene derivatives
Senkuytu, Elif; Yildirim, Tuba; Olcer, Zehra; Uludag, Yildiz; Ciftci, Gonul Yenilmez (ELSEVIER SCIENCE SA, 2018)DNA is a target molecule for anticancer drug development, and investigation on DNA interactions with synthesized potential drugs has great importance in order to discover new drug candidates, hence in this study an ... -
First paraben substituted cyclotetraphosphazene compounds and DNA interaction analysis with a new automated biosensor
Ciftci, Gonul Yenilmez; Senkuytu, Elif; Incir, Saadet Elif; Yuksel, Fatma; Olcer, Zehra; Yildirim, Tuba; Kilic, Adem; Uludag, Yildiz (ELSEVIER ADVANCED TECHNOLOGY, 2016)Cancer, as one of the leading causes of death in the world, is caused by malignant cell division and growth that depends on rapid DNA replication. To develop anti-cancer drugs this feature of cancer could be exploited by ... -
Synthesis and characterization of new cyclotriphosphazene compounds
Ciftci, Gonul Yenilmez; Ecik, Esra Tannverdi; Yildirim, Tuba; Bilgin, Kemal; Senkuytu, Elif; Yuksel, Fatma; Uludag, Yildiz; Kilic, Adem (PERGAMON-ELSEVIER SCIENCE LTD, 2013)In the present study, Spiro (1a), dispiro (1b, 2, 3), per-substituted spermine-bridged (6-9) and dispiroansa spermine (10) derivatives of cyclotriphosphazene have been synthesized. The structures of the novel compounds ... -
Synthesis, cytotoxicity and apoptosis of cyclotriphosphazene compounds as anti-cancer agents
Yildirim, Tuba; Bilgin, Kemal; Ciftci, Gonul Yenilmez; Ecik, Esra Tanriverdi; Senkuytu, Elif; Uludag, Yildiz; Tomak, Leman; Kilic, Adem (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2012)In the present study, a number of new dispirobino and dispiroansa spermine derivatives of cyclotriphosphazene (8-10, 13) were synthesized and characterized by elemental analysis, mass spectrometry, H-1 and P-31 NMR ...