Yazar "Pelit, Emel" için listeleme
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1,3-Naphthoxazine derivatives: Synthesis, in silico pharmacokinetic studies, antioxidant and photoprotective properties
Pelit, Emel; Erturk, Aliye Gediz; Gul, Melek (Academic Press Inc Elsevier Science, 2024)Investigation into the interactions between photoprotective agents and skin can offer a precise understanding of their biological behaviors in vitro and in vivo, providing crucial insights for generating new substances. ... -
alpha-Amination and the 5-exo-trig cyclization reaction of sulfur-containing Schiff bases with N-phenyltriazolinedione and their anti-lipid peroxidation activity
Pelit, Emel; Oikonomou, Kosmas; Gul, Melek; Georgiou, Dimitra; Szafert, Slawomir; Katsamakas, Sotirios; Hadjipavlou-Litina, Dimitra; Elemes, Yiannis (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)Triazolinedione quenches efficiently the 1,2-dipoles from Schiff bases of glycine esters which are formed via a [1,2-H]-prototropic shift of their alpha-hydrogens, and affords the respective alpha-aminated products in good ... -
Green Synthesis of Spiroindole Derivatives: Biological Evaluation and in Silico Studies
Pelit, Emel; Celikoglu, Umut; Gul, Melek (Taylor & Francis Ltd, 2024)This work describes the synthesis of spiro derivative compounds in the presence of nonmetallic catalysts and ultrasonic irradiation. These synthesized derivatives constitute an important class of organic compounds and ... -
A Multidisciplinary Approach to Coronavirus Disease (COVID-19)
Erturk, Aliye Gediz; Sahin, Arzu; Ay, Ebru Bati; Pelit, Emel; Bagdatli, Emine; Kulu, Irem; Gul, Melek (Mdpi, 2021)Since December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority ... -
Synthesis of PhTAD-substituted dihydropyrrole derivatives via stereospecific C-H amination
Gul, Melek; Elemes, Yiannis; Pelit, Emel; Dernektsi, Eleni; Georgiou, Dimitra; Oikonomou, Kosmas; Lis, Tadeusz; Szafert, Slawomir (SPRINGER, 2017)Stereospecific alpha-amination has been accomplished via addition of N-phenyltriazolinedione (PhTAD) to the allylic position of dihydropyrroles. The aim of this study is to evaluate new PhTAD derivatives of biologically ... -
Synthesis, antimicrobial activity and molecular docking studies of spiroquinoline-indoline-dione and spiropyrazolo-indoline-dione derivatives
Gul, Melek; Celikoglu, Emine Turk; Idil, Onder; Tas, Gamze; Pelit, Emel (Nature Portfolio, 2023)Spiro[benzo[h]quinoline-7,3 '-indoline]diones and spiro[indoline-3,4 '-pyrazolo[3,4-b]quinoline]diones were efficiently synthesized via one-pot multi-component reactions under ultrasound-promoted conditions. Spiro[benzo[ ...