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Acute treadmill exercise induces mitochondrial unfolded protein response in skeletal muscle of male rats
Turkel, Ibrahim; Kubat, Gokhan Burcin; Fatsa, Tugba; Acet, Ozgu; Ozerklig, Berkay; Yazgan, Burak; Simsek, Gulcin (Elsevier, 2025)Mitochondria are often referred to as the energy centers of the cell and are recognized as key players in signal transduction, sensing, and responding to internal and external stimuli. Under stress conditions, the mitochondrial ... -
Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines
Turkel, Ibrahim; Ozerklig, Berkay; Atakan, Muhammed M.; Aktitiz, Selin; Kosar, Sukran N.; Yazgan, Burak (Bentham Science Publ Ltd, 2022)Physical inactivity is a major cause of chronic diseases. It shortens the health span by lowering the age of the first chronic disease onset, which leads to decreased quality of life and increased mortality risk. On the ... -
Systemic and tissue-specific spexin response to acute treadmill exercise in rats
Turkel, Ibrahim; Ozerklig, Berkay; Yazgan, Burak; Ozenc, Ahmet Emrah; Kubat, Gokhan Burcin; Simsek, Gulcin; Atakan, Muhammed Mustafa (Elsevier Science Inc, 2024)Spexin (SPX) is a 14-amino-acid peptide that plays an important role in the regulation of metabolism and energy homeostasis. It is well known that a variety of bioactive molecules released into the circulation by organs ... -
Time-course and muscle-specific gene expression of matrix metalloproteinases and inflammatory cytokines in response to acute treadmill exercise in rats
Turkel, Ibrahim; Tahtalioglu, Sema; Celik, Ertugrul; Yazgan, Burak; Kubat, Gokhan Burcin; Ozerklig, Berkay; Kosar, Sukran Nazan (Springer, 2024)BackgroundThe extracellular matrix (ECM) of skeletal muscle plays a pivotal role in tissue repair and growth, and its remodeling tightly regulated by matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases ...
