Yazar "Nursal, Ayse Feyda" için listeleme
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Analysis of Endotheal Nitric Oxide Synthase Gene VNTR Variant in Turkish FMF Patients
Turkeli, Ozlem Sezer; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Galenos Publ House, 2022)Objective: Familial Mediterranean fever (FMF), caused by the MEFV gene encoding pyrin, is a prevalent monogenic autoinflammatory disease. Nitric oxide (NO), synthesized by nitric oxide synthase (NOS) is a gaseous free ... -
Association of ACE ID, MTHFR C677T, and MIF-173GC variants with the clinical course of COVID-19 patients
Tekcan, Akin; Cihangiroglu, Mustafa; Capraz, Mustafa; Capraz, Aylin; Yigit, Serbuelent; Nursal, Ayse Feyda; Menekse, Elif (Taylor & Francis Inc, 2023)The course of coronavirus disease-2019 (COVID-19) differs from person to person. The relationship between the genetic variations of the host and the course of COVID-19 has been a matter of interest. In this study, we ... -
Circadian clock gene variants may affect circadian fluctuations of anaerobic performance Gene variants and performance
Atan, Tulin; Unver, Saban; Nursal, Ayse Feyda; Yigit, Serbulent; Tekcan, Akin (Bayrakol Medical Publisher, 2021)Aim: Circadian rhythm (CR) may be followed by almost all biochemical and physiological processes that occur in the human body. Physical activities involving anaerobic fitness have displayed a dear CR. The aim of this study ... -
Effect of IL-6-174G/C and-572G/C variants on susceptibility to osteoarthritis in Turkish population
Yigit, Serbulent; Tekcan, Akin; Inanir, Ahmet; Nursal, Ayse Feyda; Akkanat, Songul; Tural, Ercan (Taylor & Francis Inc, 2022)Osteoarthritis (OA) is a complex disorder characterized by degenerative articular cartilage in which inflammatory mechanisms play a major role in the pathogenesis. Interleukin-6 (IL6), a multifunctional cytokine, can trigger ... -
The effect of the MBL2 gene rs1800450 variant on COVID-19 development in Turkish patients
Capraz, Mustafa; Tekcan, Akin; Cihangiroglu, Mustafa; Nursal, Ayse Feyda; Capraz, Aylin; Menekse, Elif; Demir, Hatice Dortok (Taylor & Francis Inc, 2025)The coronavirus disease 2019 (COVID-19) is a recent pandemic occurring worldwide due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, spreading mainly through large respiratory droplets or maybe ... -
Evaluating interleukin-6 levels and the rs1800795 variant in Turkish patients with COVID-19: a prospective cohort study
Sezer, Ozlem; Nursal, Ayse Feyda; Gunal, Ozgur; Gorgun, Selim; Tekcan, Akin; Unluguzel Ustun, Goksenin; Yigit, Serbulent (Taylor & Francis Inc, 2023)BackgroundCoronavirus disease 2019 (COVID-19) is a multisystem disease of global significance. Interleukin (IL)-6 is a soluble cytokine with a pleiotropic effect on inflammation and the immune response.ObjectivesInvestigate ... -
Genetic association of the BsmI variant of vitamin D receptor gene with risk of morbid obesity
Ozsoy, Seyma; Yigit, Serbulent; Nursal, Ayse Feyda; Ozsoy, Zeki; Dasiran, Mehmet Fatih; Daldal, Emin; Tekcan, Akin (Assoc Medica Brasileira, 2024)OBJECTIVE: The aim of this study was to evaluate the vitamin D receptor (VDR) BsmI variant in morbidly obese patients compared with healthy normal controls. METHODS: The study included 103 patients with morbid obesity and ... -
Lack of association between VNTR variant of the circadian gene (PER3) and major depressive disorder in a sample of a Turkish population
Yigit, Serbulent; Nursal, Ayse Feyda; Ozsoy, Filiz; Duman, Esra; Ustaoglu, Melih Sercan (Taylor & Francis Inc, 2023)Major depressive disorder (MDD), which is a prevalent psychiatric disorder, is characterized by sleep-wake disturbances. An underlying circadian rhythm disorder mainly may cause these disturbances. The study presented here ... -
miR-146a rs2910164 (G/C) variant may predict morbid obesity risk in adults
Ozsoy, Zeki; Nursal, Ayse Feyda; Ozsoy, Seyma; Tekcan, Akin; Yigit, Serbulent (Taylor & Francis Inc, 2024)Obesity is a common public health problem associated with serious, life-threatening complications. MicroRNAs (miRs) have modulating roles in the immune and inflammatory systems. Therefore, this study aimed to analyze the ... -
Role of Interleukin-6 Gene Variants in the Development of Oral Squamous Cell Carcinoma
Gumusay, Ozge; Yigit, Serbulent; Nursal, Ayse Feyda; Tekcan, Akin; Dagmura, Hasan; Kuruca, Nilufer (Kare Publ, 2022)Oral squamous cell carcinoma (OSCC), with its low survival rates and increasing incidence, is due to various etiological factors including environmental, genetic, and epigenetic changes. Interleukin 6 (IL 6) is a cytokine ...