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Trimetazidine alone or in combination with gemcitabine and/or abraxane decreased cell viability, migration and ATP levels and induced apoptosis of human pancreatic cells
Sekeroglu, Vedat Atli; Sekeroglu, Vedat; Isik, Sevil; Aydin, Birsen (Elsevier Masson, Corp Off, 2021)Background: Trimetazidine (TMZ) is an anti-ischemic agent that can inhibit the fatty acid oxi-dation. It has been stated that inhibition of fatty acid oxidation may be an acceptable approach to cancer treatment. Methods: ...