Yazar "Gül, Melek" için listeleme
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Antiproliferative Activity of Pyrrolidine Derivatives compound in Colon Cancer Cells
Gül, Melek; Yıldırım, Tuba; Mesci, Seda (2022)Objective: Anti-cancer drug research plays an important role for chemotherapeutic treatments in various types of cancer. Pyrolidine derived compounds have been reported by many researchers to be a potent anti-cancer compound. ... -
ATP?Binding Cassette Transporters Mediated Chemoresistance in MCF-7 Cells: Modulation by PhTAD-Substituted Dihydropyrrole Compounds
Purpose: ABC proteins transport many substrates such as antibiotics and drugs. Increase of ABCs lead chemoresistance in can-cer.In view of this information, in our study, we planned to investigate both PhTAD-substituted ... -
Effects of Sulfur Containing Glycine Imine Derivatives Compounds on Multidrug Resistance Proteins (MRPs) and Apoptosis Mechanism in MCF-7 and DLD-1 Cell Lines
Gül, Melek; Yıldırım, Tuba; Mesci, Seda; Yazgan, Burak; b, a (2022)Objective: Glutathione (GSH) is a tripeptide consisting of glycine, glutamic acid and cysteine. If the sulfur containing amino acids like methionine and cysteine increase in the cells, the level of GSH increases. GSH is ... -
PhTAD-Substituted Dihydropyrrole Compounds Regulate Apoptotic Cell Death in MCF-7 Cells
Breast cancer is the most common type of cancer amongst women. Apoptosis is known as a programmed cell death and this mechanism induces cancer cell death. Dihydropyrrole compounds contain a heterocyclic structure and these ... -
Yeni fulleren sentezi türevli organik bileşiklerin
Kozak, Zehra (Amasya Üniversitesi, 2017)1985 yılında keşfedilen ve 1990 yılından itibaren kullanılmaya başlanılan fullerenler yeni bir araştırma alanı olarak çok ilgi çekmektedir. Fullerenler transistör özelliklerinin yanı sıra güneş hücrelerinde de aktif olarak ...