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Novel Tricyclo[4.2.1]Nonane and Bicyclo[2.2.1]Heptane Derivatives: Synthesis, in Vitro Biological Activities and in Silico Studies
Sarikaya, Meryem Kececi; Yaglioglu, Ayse Sahin; Ceylan, Mustafa; Yirtici, Uemit (Wiley-V C H Verlag Gmbh, 2025)The target benzothiazole derivatives (8a-g) were synthesized starting from norbornene. The addition of dichloroketene to norbornene followed by the reduction of chlorine atoms were synthesized tricyclo[4.2.1.02,5]non-7-en-3-one ... -
Synthesis of (E)-7-arylidene-5-(hydroxy(aryl)methyl)bicyclo[3.2.0] heptan-6-one derivatives as anti-cancer agents
Ceylan, Mustafa; Zorlu, Bahar; Şahin, Ayşe; Akdoğan, Nuray; Gürdere, Meliha Burcu; Keçeci Sarıkaya, Meryem; Budak, Yakup (2023)7,7-Dichlorobicyclo [3.2.0]heptan-6-one was prepared by adding dichloroketene to cyclopentene. Reduction of 7,7-dichlorobicyclo[3.2.0]heptan-6-one with Zn in acetic acid afforded the bicyclo[3.2.0]heptan-6-one. ...