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Gabriel-Cromwell aziridination of amino sugars; chiral ferrocenoyl-aziridinyl sugar synthesis and their biological evaluation
Sert, Mustafa; Isilar, Ozer; Yaglioglu, Ayse Sahin; Bulut, Adnan (Elsevier Sci Ltd, 2021)N-sugar substituted chiral aziridines were synthesized via Gabriel-Cromwell reaction. Novel pure diastereomers of aziridine derivatives (4 diastereomers) were readily obtained in high yields and their structures were ... -
The Synthesis and Anti-cancer Activities of Ferrocenyl Chalcones; Drug-Likeness Calculations
Albayrak, Emine; Işılar, Özer; Bıyıkoğlu, Mutluhan; Yağlıoğlu, Ayşe Şahin; Bulut, Adnan (Kırıkkale Üniversitesi, 2021)A series of 1-8 different ferrocenyl chalcones were synthesized through the Claisen–Schmidt condensation and the Friedel−Crafts acylation. Their structures were confirmed by means of 1H, 13C NMR and FT-IR. The cytotoxic ...