Food Additives and Genotoxicity

Abstract

In today's changing conditions, there has been an increase in the consumption of ready-made food with the change in eating habits. Moreover, parallel to the increase in ready-made food production, there has been an increase in the food additives used. The dose amounts of food additives are determined as a result of experimental analyses. However, some additives show long-term toxic effects on the human body in genotoxicity tests. In this review, definition of substances, purposes of usage, classification, genotoxicity, definitions of tests and publications of genotoxicity studies in food additives were discussed. The search was conducted in peer-reviewed journals using Science-Direct, Web of Science and Google Scholar. In this study, genotoxicity studies conducted with food additives between 2015-2021 were complied. For this purpose, the keywords ‘‘food additive’’, ‘‘genotoxicity’’ were used together and research articles were included in this study.