Relationship of atherogenic index of plasma with exercise, obesity and biochemical parameters

Abstract

Aims: It is well-known that regular moderate-intensity aerobic exercise has positive effects on various health indicators, including obesity and cardiovascular diseases (CVD) and atherogenic index of plasma (AIP) is defined as a highly sensitive predictor of plasma atherogenicity and cardiovascular risk. Furthermore, it is known that physical activity has a reducing effect on AIP with its ability to decrease visceral fat and its positive impact on blood lipids. Additionally, large-scale AIP screenings are recommended for the early detection of obese individuals and effective intervention. This study aims to determine the relationship between regular exercise and cardiometabolic parameters and obesity based on current data. Methods: The study involved a total of 126 participants aged 18-65 and it was conducted in the form of file screening, where the medical history reports of all patients were examined, and systemic physical findings were assessed. Fasting blood samples were used to determine the lipid profile. Anthropometric measurements and biochemical parameters of the participants were determined and AIP was calculated using the formula AIP=log10 (TG/HDL-C). Participants were categorized into groups based on their exercise status, BMI, and AIP risks, and the data of the study groups were evaluated statistically. Results: Participants were divided into two groups based on exercise status, and in the exercise group, body mass index (BMI), body weight, waist circumference, AIP, and triglyceride levels were found to be lower, while high-density lipoprotein (HDL) levels were higher compared to the non-exercise group. In all participants, moderate-intensity exercise was negatively correlated with AIP, body weight, BMI, waist circumference, triglyceride, and low-density lipoprotein (LDL) levels; and positively correlated with HDL levels. Conclusion: The relationships uncovered in this study among exercise, cardiometabolic parameters, and obesity status are expected to contribute to future research, especially in studies focusing on the impact of exercise on CVD and obesity.