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Adropin and spexin hormones regulate the systemic inflammation in adenine-induced chronic kidney failure in rat
(Wolters Kluwer Medknow Publications, 2021)
Chronic kidney disease is one of the major global health problems. Chronic renal failure is stimulated by many cytokines and chemokines. Adropin and spexin (SPX) are peptides hormones. These peptides could affect inflammatory ...
Explorations of ATP-Binding Cassette Transporters and Apoptosis Signal Pathways of 2-Hydroxyanthraquinone Substituted Cyclotriphosphazenes in MCF-7 and DLD-1 Cell Lines
(Bentham Science Publ Ltd, 2022)
Background: As a class with biological properties, such as anti-cancer, anti-bacterial, anti-HIV, and various physical effects, phosphazene derivatives constitute the most striking part of inorganic compounds. Anthraquinones, ...
EXAMINATION OF CORRELATIONS BETWEEN VITAMIN D AND MELATONIN LEVELS WITH SLEEP AMONG WOMEN AGED 18-49 YEARS
(Natl Inst Public Health, 2023)
Objectives: Although clinical research is still going on to determine any relationship between vitamin D and sleep regulation, only few studies have identified the role of vitamin D metabolism in sleep disorders. The current ...
Antioxidant, Cytotoxic Activity and Pharmacokinetic Studies by Swiss Adme, Molinspiration, Osiris and DFT of PhTAD-substituted Dihydropyrrole Derivatives
(Bentham Science Publ Ltd, 2022)
Background: Pyrrole compounds having a heterocyclic structure are the most researched and biological activities such as antioxidant and anticancer activities. Objective: Herein is a first effort to study the significance ...
Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin
(Sage Publications Ltd, 2021)
Chronic kidney disease is a major global public health problem. The peptide hormones adropin and spexin modulate many physiological functions such as energy balance and glucose, lipid and protein metabolism. However, it ...
Impact of spexin on metabolic diseases and inflammation: An updated minireview
(Sage Publications Ltd, 2022)
Spexin (SPX) is a 14 amino acid length peptide hormone which was discovered using bioinformatic tools. It is extensively expressed in central and peripheral tissues and secreted into circulation in response to metabolic ...
Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines
(Bentham Science Publ Ltd, 2022)
Physical inactivity is a major cause of chronic diseases. It shortens the health span by lowering the age of the first chronic disease onset, which leads to decreased quality of life and increased mortality risk. On the ...