https://hdl.handle.net/20.500.12450/11 Other Units 2026-04-06T01:12:46Z https://hdl.handle.net/20.500.12450/5777 Medicolegal evaluation of geriatric deaths in Bursa, Turkey Çetin, Selçuk; Baduroğlu, Erol; Gök, Ertuğrul; Fedakar, Recep; Öner, Bedirhan Sezer Aim: Differentiation of natural and forced deaths observed in this age group is very important in the forensic medicine practice. According to the address based population registration system, population rate of 65 years and older has been 9.5% of the total population in 2020. In the present study, we aimed to medicolegal evaluation of demographic data and autopsy findings of judicial geriatric deaths in Bursa and around.Material and Method: Autopsy reports of the cases who have been taken to Morgue Specialization Office of Council of Forensic Medicine Institution and at 65 years and over, crime scene and deceased examination reports and data in the prosecution documents were assessed retrospectively between 2003-2008 in our study. Results: During 6-year period, totally 5155 autopsies have been investigated in Morg Specialization Office of Bursa Council of Forensic Medicine Institution. Among such cases, 870 (16.8%) were 65 years old and older. Cases who were 65 years old and older included 640 (73.6%) were male, 230 (26.4%) were female. In terms of death origin, 434 (49.9%) were natural deaths, 267 (30.7%) were accidents, 102 (11.7%) were suicides and 52 (6%) were homicides. Origin of death of the remaining 15 (1.7%) could not be detected. According to the information obtained from the statements of the witnesses in crime scene investigation and dead body examination reports, a previous disease existed in 336 (38.6%) cases before death. Diseases which have been existing before death includes cardiac diseases, hypertension, central nervous system pathologies, diabetes mellitus, respiratory system pathologies, undefined psychiatric disorders, gastrointestinal system pathologies and malignancies, respectively to frequency.Conclusion: In line with prolongation of life expectancy and increase in the geriatric population, it is observed according to our outcomes that an increase is detected in judicial geriatric death cases due to neuropsychiatric disease, leading a solitary life and psychomotor imbalance. 2023-01-01T00:00:00Z https://hdl.handle.net/20.500.12450/5778 Ferritin and Cardiac Electrophysiology in End-Stage Renal Disease: Evaluating the Impact of Index of Cardio-Electrophysiological Balance Çoksevim, Metin; Kertmen, Ömer; Yıldırım, Ufuk; Türkmen, Ercan Objective: Ferritin is a critical protein involved in iron storage and functions as an acute-phase reactant, playing a significant role in chronic inflammation and the pathogenesis of cardiovascular diseases. Elevated ferritin levels in end-stage renal disease patients undergoing hemodialysis may influence cardiac electrophysiological parameters, such as the corrected index of cardio-electrophysiological balance, a marker of proarrhythmic risk. This study aimed to investigate the association between ferritin levels and the corrected index of cardio-electrophysiological balance in patients with end-stage renal disease undergoing hemodialysis. Material and Method: This retrospective cross-sectional study included 438 patients with end-stage renal disease undergoing hemodialysis, categorized into two groups according to their ferritin levels: Group 1 (≥1000 ng/mL, n=254) and Group 2 (≤200 ng/mL, n=184). Demographic, biochemical, and electrocardiographic data, including corrected index of cardio-electrophysiological balance, were analyzed. The correlation between ferritin levels and the corrected index of cardio-electrophysiological balance was assessed. Results: The index of cardio-electrophysiological balance was significantly higher in Group 1 compared to Group 2 (5.1 vs. 4.9, p=0.003). A moderate positive correlation between ferritin levels and the index of cardio-electrophysiological balance was identified (r=0.326, p; Özet Amaç: Ferritin, demir depolanmasında anahtar bir protein olup, aynı zamanda kronik inflamasyon ve kardiyovasküler hastalıklarla ilişkili bir akut faz reaktanıdır. Hemodiyaliz uygulanan son dönem böbrek yetmezliği hastalarında artan ferritin seviyelerinin, proaritmik riski yansıtan kardiyo-elektrofizyolojik denge indeksi gibi elektrokardiyografik parametreleri etkileyebileceği düşünülmektedir. Bu çalışma, hemodiyaliz alan son dönem böbrek yetersizliği hastalarında ferritin seviyeleri ile kardiyo-elektrofizyolojik denge indeksi arasındaki ilişkiyi değerlendirmeyi amaçlamaktadır. Gereç ve Yöntem: Bu retrospektif, kesitsel çalışmada, hemodiyaliz uygulanan 438 son dönem böbrek yetersizliği hastası yer almıştır. Hastalar ferritin seviyelerine göre iki gruba ayrılmıştır: Grup 1 (≥1000 ng/mL, n=254) ve Grup 2 (≤200 ng/mL, n=184). Demografik, biyokimyasal ve elektrokardiyografik veriler (kardiyo-elektrofizyolojik denge indeksi dahil) analiz edilmiştir. Ferritin seviyeleri ile kardiyo-elektrofizyolojik denge indeksi arasındaki ilişki değerlendirilmiştir. Bulgular: Kardiyo-elektrofizyolojik denge indeksi Grup 1'de Grup 2'ye kıyasla anlamlı derecede yüksek saptandı (5.1'e karşı 4.9, p=0.003). Ferritin düzeyleri ile kardiyo-elektrofizyolojik denge indeksi arasında orta düzeyde pozitif bir korelasyon tespit edilmiştir (r=0.326, p 2025-01-01T00:00:00Z https://hdl.handle.net/20.500.12450/5776 Evaluation of HBV-DNA, HCV-RNA and HDV-RNA co-existance: 2-Year retrospective study Akgün, Sadık; Sayıner, Hakan Sezgin; Tarhan, Gülnur; Akgün, İlkay Background: The aim of this study was to evaluate positivities of HBV-DNA, HCV-RNA and HDV-RNA on patients with diagnostic of chronic viral hepatitis, in our province, and to determine of togetherness of these results obtained from tests.Methods: This study was done with 4442 serum samples submitted to Microbiology laboratory of Adiyaman University Education and Training Hospital between 2013-2015 years. HBV-DNA, HCV-RNA and HDV-RNA (Fluorion, Iontek), the results obtained using qualitative and quantitative analysis kits were analyzed retrospectively. Statistical analysis was performed with SPSS 22.0.0 using by Kolmogorov-Smirnov test and chi-square analysis.Results: In this study, 2145(%55) of 3902 samples applied HBV-DNA from HBsAg positive patients samples, according to the results of ELISA test, were detected in HBV-DNA test, as positive. Eighty one (%15) of 540 samples from patient specimens found positive for anti-HCV by ELISA were detected in HCV-RNA test, as positive. Thirteen of 140 samples             (% 9.3) applied HDV-RNA test were detected as positive. Conclusions: In the study two samples were found to be positive for both HBV-DNA and HCV-RNA, four sera was found to be positive for both HBV-DNA and HDV-RNA while no sample was found to be positive for all three infections  (HBV-DNA, HCV-RNA ve HDV-RNA).; Amaç: Hepatit etkenlerinden Hepatit B, C ve D virüsü toplum sağlığı açısından ayrı bir öneme sahiptir. Bu çalışmada, ilimizde kronik viral hepatit tanılı hastalarda HBV-DNA, HCV-RNA ve HDV-RNA pozitifliğinin araştırılması ve elde edilen pozitif sonuçların birlikteliğinin değerlendirilmesi amaçlandı. Gereç ve Yöntem:  Bu çalışma 2013-205 tarihleri arasında  Adıyaman İli, Adıyaman Üniversitesi Eğitim ve Araştırma Hastanesi Mikrobiyoloji laboratuvarına gönderilen 4442 hasta serum örneğinde yapıldı.  HBV-DNA, HCV-RNA ve HDV-RNA (Fluorion HBV-QNP 2.0, HCV-QNP 2.1 ve HDV-QLP 1.0 Real-Time PCR Kiti, İontek), kalitatif ve kantitatif analiz kitleri kullanılarak elde edilen sonuçlar retrospektif olarak incelendi. İstatistiksel analiz SPSS 22.0.0'da  Kolmogorov Smirnov testi ve  Ki-kare analizi ile yapıldı.  Bulgular: ELISA sonuçlarına göre,  HBsAg pozitif örneklerden, HBV-DNA çalışılan 3902 örneğin 2145(55%)’i HBV-DNA pozitif, anti-HCV pozitif örneklerden HCV-RNA çalışılan 540 örneğin 81(%15)’inde HCV-RNA pozitif, HDV-RNA çalışılan 140 örneğin 13(%9.3)’ünde HDV-RNA pozitif saptandı. HBV-DNA ve HCV-RNA birlikte pozitifliği olan hasta sayısı iki, HBV-DNA ve HDV-RNA birlikte pozitifliği olan hasta sayısı dört, üçlü enfeksiyona ise (HBV-DNA, HCV-RNA ve HDV-RNA birlikteliğine) rastlanmadı. 2016-01-01T00:00:00Z https://hdl.handle.net/20.500.12450/5779 OVARIAN TORSION AND OVARIOPEXY IN PREGNANCY Şahin, Buğra; Cura, Gizem; Çelik, Fatih; Şahin, Banuhan A patient, aged 28 years and 33 weeks of pregnancy, admitted to our center with severe left lower quadrant pain. Ovarian torsion due to a 9 cm left ovary cyst was prediagnosed. The patient underwent general anesthesia and was corrected for torsioned ovary, blood was supplied, and the ovary was successfully fixed to the uterus by ovariopexy in order to avoid recurrence of torsion. The baby was born with a cesarean section. The patient was called to the control on the fifteenth day postop and the blood flow was re-evaluated by doppler ultrasonography. Although antepartum surgery is considered safe, abdominal surgery carries some risks for a pregnant woman and the fetus. Therefore, the clinical decision should be made according to the characteristics of the adnexal mass, the pregnancy week, pregnancy expectancy and reperfusion of the ovary.; Yirmi sekiz yaşında, gebeliğinin 33. haftasında olan bir hasta merkezimize ciddi sol alt kadran ağrısı ile başvurdu. Dokuz cm boyutundaki sol over kistine bağlı over torsiyonu ön tanısı kondu. Genel anestezi altında torsiyone over düzeltilerek kanlanması sağlandı ve tekrardan torsiyone olmaması için ovaryopeksi operasyonu ile over uterusa sabitlendi. Bebek sezaryen ile doğurtuldu. Hasta, post op on beşinci gününde kontrole çağrıldı ve dopler ultrasonografi ile over kan akımı yeniden değerlendirildi. Antepartum cerrahi müdahale güvenli kabul edildiği halde, abdominal cerrahi gebe bir kadın ve fetus için bazı riskler taşır. Bu yüzden klinik karar, adneksiyal kitlenin karakteri, gebelik haftası, gebelik beklentisi ve overin tekrar kanlanmasına göre verilmelidir. 2018-01-01T00:00:00Z