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Synthesis and characterization of new cyclotriphosphazene compounds

Ciftci, Gonul Yenilmez; Ecik, Esra Tannverdi; Yildirim, Tuba; Bilgin, Kemal; Senkuytu, Elif; Yuksel, Fatma; Uludag, Yildiz; Kilic, Adem (PERGAMON-ELSEVIER SCIENCE LTD, 2013)

In the present study, Spiro (1a), dispiro (1b, 2, 3), per-substituted spermine-bridged (6-9) and dispiroansa spermine (10) derivatives of cyclotriphosphazene have been synthesized. The structures of the novel compounds ...

Synthesis, cytotoxicity and apoptosis of cyclotriphosphazene compounds as anti-cancer agents

Yildirim, Tuba; Bilgin, Kemal; Ciftci, Gonul Yenilmez; Ecik, Esra Tanriverdi; Senkuytu, Elif; Uludag, Yildiz; Tomak, Leman; Kilic, Adem (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2012)

In the present study, a number of new dispirobino and dispiroansa spermine derivatives of cyclotriphosphazene (8-10, 13) were synthesized and characterized by elemental analysis, mass spectrometry, H-1 and P-31 NMR ...

The bioactive new type paraben decorated dispiro-cyclotriphosphaze compounds: synthesis, characterization and cytotoxic activity studies

Senkuytu, Elif; Akbas, Nadide; Yildirim, Tuba; Ciftci, Gonul Yenilmez (Elsevier, 2022)

Cancer is a leading cause of death worldwide and hence studies to find anti-cancer agents for its treatment continue to grow in importance. Generally, cytotoxic drugs have been used for cancer treatment in susceptible ...

The first synthesis and characterization of spiro and ansa-cyclotriphosphazenes with 3-Hydroxyflavone and induction of apoptosis in breast cancer (MCF-7)

Ciftci, Gonul Yenilmez; Koksal, Burak; Kitmur, Ibrahim; Mesci, Seda; Ay, Ebru Bati; Yildirim, Tuba (Elsevier, 2024)

In this study, the first series of 3-Hydroxyflavone substituted spiro, ansa-1,3-propanedioxy and 2,2-dimethyl 1,3propanedioxy substituted cyclotriphosphazene compounds 912 were synthesized and their structures were ...